The Effect of Chlorhexidine on Ventilatory Patient in ICU

Identifying Research Methodologies

Grap, M. J., Munro, C. L., Hamilton, V. A., Elswick Jr, R. K., Sessler, C. N., & Ward, K. R. (2011). Early, single chlorhexidine application reduces ventilator-associated pneumonia in trauma patients. Heart & Lung: The Journal of Acute and Critical Care40(5), e115-e122.

Reasons for Choosing the Article

The study by Grap et al. (2011) was chosen because it addresses the issue, which is the relationship between ventilator-acquired pneumonia and the effect of chlorhexidine oral microbial flora.

Goals of the Study

The study’s objective was to compare the impact of early (within 12 hours of intubation) or control (no swab) administration of chlorhexidine on oral microbial flora and ventilator-acquired pneumonia.


Research Techniques

Grap et al. (2011) gathered data using a quantitative research technique. One hundred forty-five trauma patients made up the sample for the researchers’ experimental study. Participants were randomly assigned to treatment and control groups for the trial.


Research Methodology’s Strength

The study’s experimental research methodology received high marks for validity and dependability. The methodology’s success can be attributed, among other things, to the blinding throughout the assignment procedure and the random assignment of individuals to the treatment and control groups.


  1. Richards 1. (2013). Chlorhexidine-based oral hygiene regimens for patients on mechanical ventilation lower the risk of ventilator-associated pneumonia. 91–2 in Evid Based Dent., 14(3).


Reasons for Choosing the Article

The study’s focus, the role of chlorhexidine in preventing ventilator-acquired pneumonia, led to the article’s selection for the evidence-based inquiry.


Goals of the Study

The trial aimed to determine whether ventilator-acquired pneumonia in mechanically ventilated patients could be decreased by using oral hygiene regimens based on chlorhexidine.


Research Techniques

Randomized controlled trials (RCTs) were utilized by Richards (2013) to assess the effectiveness of chlorhexidine-based oral hygiene regimens. Individuals undergoing mechanical ventilation participated in the examinations.


Research Methodology’s Strength

Randomization and randomized controlled trials for a specific participant group promote the method’s internal and external validity. The questionnaire used to gather and record the data was a reliable tool, contributing to the study’s reliability.

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